(1) Background information. These agents depress the central nervous system. Patients taking these drugs should be cautioned against performing hazardous activities while under their effects.
(2) Examples of long-acting nonbarbiturate agents.
(a) Chlordiazepoxide hydrochloride (Librium®). Chlordiazepoxide is orally administered as an antianxiety agent. It is also effective when administered parenterally in the treatment of alcohol withdrawal. Side effects associated with the agent include drowsiness, ataxia, and lethargy.
(b) Oxazepam (Serax®). Oxazepam is generally less effective than either diazepam or chlordiazepoxide in the treatment of tension and anxiety. Drowsiness is the most common side effect associated with this agent.
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